The ability of Streptomyces sp. OXCI, S rimosusNRRL B2659, S. rimosusNRRL B2234, S. alboflavusNRRL B1273 S. aureofaciensNRRL B2183 and S. vendagensis ATCC 25507 to produce tetracycline using some local agricultural wastes as solid state media, were assessed.  The wastes employed include peanut (groundnut) shells, corncob, corn pomace and cassava peels.  Bacillus subtilisATCC 6633 was used to assay antimicrobial activity.  All the strains produced tetracycline in a solid-state fermentation process containing peanut (groundnut) as the carbohydrate source. Streptomyces sp. OXCI has the highest ability for tetracycline production with peanut shells as the substrate in solid fermentation (13.18 mg/g), followed by S. vendagensis ATCC 25507 (11.08 mg/g), S rimosusNRRL B1679 (8.46 mg/g), S. alboflavusNRRL B1273 (7.59 mg/g) S. rimosusNRRL B2234 (6.37 mg/g), S. aureofaciens NRRL B2183 (4.27 mg/g).  Peanut (groundnut) shells were the most effective substrate (4.36 mg/g) followed by corncob (2.64 mg/g), cassava peels (2.16 mg/g) and corn pomace (1.99 mg/g).  The composition of the peanut (groundnut) shell medium optimal for tetracycline production were peanut shells 100 g, organic nitrogen (peanut meal) 10 g, (NH4)2SO4 1g, KH2PO4 0.5 g, CaCO3 0.5 g, NaCI 0.5 g, MgSO4 7H2O 0.5 g, soluble starch 10 g, peanut oil 0.25 ml with initial moisture content of 65-68%, and initial pH 5.3.  Substrate (1 g dry weight) was inoculated with 1.0 X 108 conidia per ml and incubated at 28-31 oC for 5-7 days, producing 13.18 mg/g of total tetracycline.  Tetracycline detection stated on day 3 and attained its maximum level on day 5.

-         Seminar presentations (3 times)

-         A research report submitted to FIIRO library

-         Seven (7) papers published in referred Journals